Is your pain coming from a nerve or muscle?
- Daniel O’Quinn
- Apr 4
- 3 min read
Whether you're an athlete, clinician, or just someone trying to figure out why your leg hurts after a run, knowing the difference between a muscle strain and a nerve injury is essential. While they can feel similar at times, these two types of injuries require very different treatment approaches. Here's a breakdown of how to spot the difference, along with practical advice for both self-testing and treatment.
Understanding Muscle Strains
Muscle strains are classified into three grades:
Grade 1 (Mild):
Minor muscle fiber damage
Mild soreness and tightness
No visible bruising or swelling
Full strength and function remain intact
Usually heals within a few days to two weeks
Grade 2 (Moderate):
Partial muscle fiber tearing
Noticeable swelling, bruising, and weakness
Some loss of strength or range of motion
May require imaging (like an MRI)
Grade 3 (Severe):
Complete muscle rupture or avulsion (where muscle detaches from bone)
Severe pain, swelling, and bruising
Significant loss of strength and function
Often includes a visible “recoil” or bulge in the muscle
Likely requires surgery or extended rehab
Understanding Nerve Injuries
Nerve injuries fall into three main categories:
Neuropraxia (Mild):
Temporary blockage of nerve signals due to pressure or traction
No structural damage to the nerve
Common with awkward positions or minor trauma
Recovery usually takes days to weeks
Axonotmesis (Moderate):
Damage to nerve fibers (axons) with the surrounding sheath intact
Caused by more severe or repetitive traction or compression
Symptoms include pain, numbness, and tingling
Recovery occurs via nerve regeneration: about 1 mm/day or 1 inch/month
Neurotmesis (Severe):
Complete disruption of the nerve structure
Often results from crush injuries or severe trauma
Recovery is minimal even with surgical intervention
Real-World Example: The Baseball Player
Imagine a baseball player rounding first base, suddenly feeling a pop in his hamstring. No visible bruising, just pain and reduced motion. Is it a mild muscle strain—or something more?
In this case, further testing revealed signs of a Grade 1 strain of the biceps femoris, along with a nerve sensitivity issue likely caused by traction on the sciatic nerve. Treatment focused on calming down the nerve irritation and gradually reintroducing movement.
Self-Testing at Home
Here are a few tests to help differentiate between muscle and nerve issues:
1. Toe Touch Test
Used to assess hamstring or posterior chain discomfort
Pain from either muscle strain or nerve irritation may show up here
2. Slump Test
Sit, round your back and neck without moving your legs
If symptoms appear in your leg during this, it points more toward nerve irritation
3. Extension-Based Movements
Repeated back extensions (like cobra stretches)
If symptoms improve, this may indicate a spinal or nerve component rather than a pure muscle issue
How to Treat Each Injury Type
For Muscle Strains:
Avoid complete rest — gentle movement is key
Progressive loading helps tissue heal better and faster
Stretching and strengthening must be balanced to avoid reinjury
For Nerve Injuries:
Use nerve glides or flossing techniques to improve nerve mobility
Focus on reducing surrounding tissue tension
Movement provides blood flow and nutrients essential for healing
Key Takeaways
Muscle strains show more visible signs (swelling, bruising) and respond well to progressive loading.
Nerve injuries involve neurological symptoms (numbness, tingling) and often require different movement strategies.
Simple home tests like the slump test can give you insight into the source of your pain.
Accurate diagnosis matters — it affects treatment and recovery timeline.
Early movement is critical for both types, but must be done with care and intention.
By understanding the core differences between muscle and nerve injuries, you can make smarter decisions about your recovery and avoid setbacks. And if you're ever unsure, seek guidance from a trained clinician who understands both sides of the equation.
Stay active. Stay informed. And when in doubt — test, don't guess.

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